Technology
HOw it works

The ImplantStim™ technology is based on pioneering patents and patent pending
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Patented bioelectric signaling sequence for controlling OPG expression for osseointegration

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Patent pending bioelectric sequence for controlling KLOTHO expression.

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Patented bioelectric signaling sequence for controlling RANKL expression.

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Patent pending bioelectric sequence for controlling IGF1 expression.

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Patented combination of bioelectics and biologics for accelerated healing.

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Patent pending bioelectric PRF combination.

Patented
Method wherein bioelectric stimulation device causes OPG release to enhance osteoblast formation and bone formation/re-mineralization for tooth stability
ImplantStim™ via Leonhardt’s Launchpads and DentaCell Accelerator has an exclusive license to over 400 bioelectric and biologics related healing patent and patent-pending patent claims.
The Leonhardt Patents
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The Chalmers Patent
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The Schüler Patents
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The Leonhardt, Miron, Kanter Patent Pending
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Patented
A system to selectively administer electrical stimuli to a patient, comprising: a programmable source of variable frequency, variable amplitude electrical signals, whereby the frequency is capable of being varied within a range of approximately 0.1 to 970 hertz and the amplitude is capable of being varied within a range of approximately 20 to 400 microamps; and a plurality of electrodes to connect the source to a patient, whereby the variable frequency, variable amplitude electrical signals are applied as electrical stimuli to a region proximate to the mouth of the patient to perform a predetermined protocol
The ImplantStim™ Generation I bioelectric stimulator manufactured by Mettler Electronics of Anaheim, California for ImplantStim on an OEM basis has FDA 510K K113017 market clearance already for improving blood circulation and pain relief.
The ImplantStim engineering team is developing three products:
  1. ImplantStim™ – Bioelectric stimulation controlled protein expressions for accelerated healing.
  2. ImplantStim™ Wireless – Wireless electromagnetic energy controlled protein expressions for accelerator healing .
  3. ImplantStim™ Plus – Bioelectric stimulation + IS-15 proprietary biologics composition for accelerated healing including patent pending Bioelectric PRF TM and regenerative fluid derived from amniotic fluid and exosomes.

Target Goals of the ImplantStim Therapy

  • 70% Improvement of bone formation (osteogenesis)
  • 400% Acceleration of the healing process via osteointegration by controlled bioelectric release of OPG and other healing promoting proteins.
  • 70% Reduction of pain an discomfort
  • 50% Increase in bone to implant (BIC)
  • 70% Increase in trabecular bone volume density
  • Reduce the need for repeat/repair surgeries
The ImplantStim™ controlled bioelectric protein expressions technology is designed to actively stimulate, accelerate and improve osteogenesis (bone formation) by 70% and is intended to accelerate osseointegration (bone to implant connection) by up to 400%, this even proven successful in clinical studies will shorten the healing time by 2/3rds after implant placement as well as enabling the loading of the implant (crown placement) after only 1/3 of the usual time.
The ImplantStim™ technology may be a suitable alternative for patients who may not normally be considered good candidates for implants with poor bone quality from underlying diabetes or other autoimmune disorders as well as heavy smokers and drinkers.
ImplantStim Conductive Bioelectric Mouthpiece Prototype Used in Pilot Studies and Lab Testing